Research Scientist
Job Number: 23-02168
Be part of a company that delivers life - changing healthcare solutions. Eclaro is looking for a Research Scientist for our client in San Diego, CA.
Eclaro’s client is among the world’s largest pharmaceutical companies, trusted by billions to provide superior, cutting-edge, and inexpensive medicine that improves health and well-being. If you’re up to the challenge, then take a chance at this rewarding opportunity!
Responsibilities:
- Utilize and develop multiple disease models to design target validation studies and relevant assays in support of SAR, mechanism of action, mechanisms of resistance, biomarker selection, and disease positioning.
- Develop and implement cell-based assays to address both tumor intrinsic cellular biology and immune-based mechanisms of action for potential drug candidates
- Design and conduct essential mechanistic experiments in cell biology, cellular biochemistry, molecular biology, and assay development
- Accurately maintain written reports and present results in an organized and timely manner.
- Communicate effectively, foster teamwork, and contribute to collaborative efforts.
- Strong commitment to quality and demonstrate adaptability.
Required Qualifications:
- Knowledge and experience in using multi-parameter flow cytometry
- Hands-on experience with mammalian cell culture, molecular and cellular technologies (e.g., CRISPR / Cas9 knock-in / out, lentiviral transduction, western blotting, quantitative PCR,) and functional assays (e.g., proliferation, apoptosis, cell cycle) is essential
- Ph.D. in cell biology, immunology, molecular biology, or equivalent field with 0-2 years of post-doc or industry experience, or M.S. degree with 3+ years of experience, or Bachelors degree with 5+ years of experience in the biopharmaceutical industry developing and optimizing cell-based assays, preferably in Oncology
- Strong background and experience in cancer research with training in molecular and cell biology
- Extensive experience using multi-parameter flow cytometry in the context of primary immune cell isolation and characterization is required.
- Extensive hands-on experience with mammalian cell culture, molecular and cellular technologies (e.g., CRISPR / Cas9 knock-in / out, lentiviral transduction, western blotting, quantitative PCR,) and functional assays (e.g., proliferation, apoptosis, cell cycle) is essential
- Experience in utilizing platforms including IncuCyte, JESS, Flow based cell sorter, ELISA, and MSD in the context of oncology-based drug discovery is a plus.
Skills:
- Strong record of high-impact and rigorous science though publication history.
- Proficiency in scientific data analysis programs including GraphPad Prism, FlowJo, Microsoft Excel / PowerPoint, is required
- Capability to deliver high quality data in an organized and timely manner
- Ability to work in a fast-paced dynamic team environment; flexibility to adapt to changes with a positive attitude and independently collaborate across teams, requiring excellent communication skills, both written and verbal, with strong interpersonal skills.
If hired, you will enjoy the following Eclaro Benefits:
- 401k Retirement Savings Plan administered by Merrill Lynch
- Commuter Check Pretax Commuter Benefits
- Eligibility to purchase Medical, Dental & Vision Insurance through Eclaro
If interested, you may contact:
Moneth Rojas
moneth.rojas@eclaro.com
516-386-3714
Equal Opportunity Employer: Eclaro values diversity and does not discriminate based on Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status. •
Last updated on Aug 22, 2023