Laboratory and Facilities Manager

Achilles Therapeutics is a high growth clinical-stage biopharmaceutical company focused on the development of T cell therapies targeting clonal neoantigens for the treatment of cancer. Originating from pioneering research at Cancer Research UK (CRUK), the Francis Crick Institute and University College London (UCL), we use DNA sequencing data from each patient, together with our proprietary PELEUS™ bioinformatics platform, to identify clonal neoantigens specific to that patient. From this, we develop personalised T cell therapies and currently have two programs in the clinic for the treatment of Non-Small Cell Lung Cancer and Metastatic Malignant Melanoma.

As a company, we are fast-paced and trailblazing. We are breaking new ground with our science, creating products that have never been made. As no-one has done what we are doing before, there is no playbook to copy. This means we must innovate, adapt and collaborate across our organisation, working together to solve novel problems. This entrepreneurial spirit and approach run through our company and those who thrive here are able to cope with anything that is thrown at them, enjoy ambiguity and thrive on making things happen even when there is not a detailed brief. We work hard and deliver a lot.

Role Summary:

This purpose of this role is to manage the day to activities of the laboratories and offices based at the Hampstead site.

You will be involved in purchasing materials for GMP manufacturing, equipment purchasing, organisation of service visits as well as some laboratory health and safety duties.

This a permanent role based at our facility in Hampstead, London

Responsibilities:

• Manage stock control to ensure supplies are maintained at an optimal level for production operations.
• Assisting with material procurement from approved GMP suppliers.
• Ensure all materials are shipped and received in a GMP compliant and timely manner, ensuring that receipted material conforms to specifications on purchase orders and internal specifications.
• Receiving inbound deliveries of materials including ambient, 2-8 degrees Celsius and frozen material and movement of these deliveries to appropriate holding locations.
• Informing QC of material that is required to be released and ensuring materials are released in a timely manner.
• Develop and report key performance indicators, KPIs, for external suppliers and service providers.
• To assist with the management of external engineers, including inductions, arranging parking, onsite supervision and reviewing of work completed.
• When required, obtain copies of completed reports, calibration equipment and provide the critical expert review of external contractors/suppliers activities and documentation where they impact on GMP activities.
• To arrange appropriate regular laboratory cleaning and laboratory coat cleaning/delivery.
• Writing & reviewing of COSHH Risk Assessments, ensuring that all laboratory staff follow and comply with the associated COSHH and Risk Assessments associated with laboratories and assets.
• Participation in laboratory or quality meetings relating to facilities or assets.

Requirements

• Have excellent planning and organisational and time management skills.
• Self-motivated with strong initiative and drive.
• Experience of releasing materials to controlled specifications.
• Experience of working in a GMP environment
• Strong sense of urgency and ability to work in a fast-paced environment, excellent planning, organisational and time management skills, and attention to detail
• Dependable individual and willing to take ownership and responsibility
• Good communication and interpersonal skills
• Self-motivated with strong initiative and drive

Benefits

At Achilles you will enjoy a flexible and dynamic working environment that fosters creativity, leadership, and teamwork. We work hard and deliver a lot

Our benefits package includes a competitive salary and performance related bonus, group pension plan matched up to 6%, life insurance, private medical insurance, and a tax approved all employee share incentive plan.

Last updated on Oct 18, 2023