Browse
Employers / Recruiters

Senior Research Associate, Oligonucleotide Chemistry

korrobio · 30+ days ago
60 First St, Cambridge, MA 02141
Negotiable
Full-time
Continue
By pressing the button above, you agree to our Terms and Privacy Policy, and agree to receive email job alerts. You can unsubscribe anytime.
Company Summary: Korro is a biopharmaceutical company focused on developing a new class of genetic medicines for both rare and highly prevalent diseases using its proprietary RNA editing platform. Korro is generating a portfolio of differentiated programs that are designed to harness the body’s natural RNA editing process to effect a precise yet transient single base edit. By editing RNA instead of DNA, Korro is expanding the reach of genetic medicines by delivering additional precision and tunability, which has the potential for increased specificity and improved long-term tolerability. Using an oligonucleotide-based approach, Korro expects to bring its medicines to patients by leveraging its proprietary platform with precedented delivery modalities, manufacturing know-how, and established regulatory pathways of approved oligonucleotide drugs. Korro’s lead program is Alpha-1 Antitrypsin Deficiency (AATD). Korro is based in Cambridge, Massachusetts.

We are collaborative and united by a common mission. We are building a company with extraordinary people with an audacious vision to create transformative genetic medicines for prevalent diseases. Our values - Rewrite the future, On the Cutting Edge, Better Together, Dynamically Different, Kindness and Integrity form the fabric of the organization. They are reinforced daily and serve as key dimensions in the hiring process to help us ensure that Korro is a magnet for outstanding talent and a great place to work. Join us as we redefine what's possible in genetic medicine and work to make a lasting impact on human health.

Position Summary:  Korro Bio is seeking a passionate, driven, and creative chemist to join our oligonucleotide chemistry team and work with an enthusiastic team of highly skilled scientists in a dynamic, growing company. The successful candidate will have a strong background in oligonucleotide chemistry and will be responsible for the synthesis, purification and analysis of novel oligonucleotides and oligonucleotide conjugates to advance our RNA editing drug discovery programs. Candidate must express a high attention to detail, be comfortable multitasking and be able to function in an interdisciplinary and fast-paced startup environment.  

Key Responsibilities:

  • Execute solid-phase synthesis, purification, and downstream processing of chemically modified oligonucleotides and oligonucleotides conjugates at different scales using modern automated oligo synthesis platforms.
  • Operate, maintain & troubleshoot equipment for oligonucleotide synthesis (Mermade 12), purification (ӒKTA Pure), desalting and lyophilization.
  • Ability to cross-train with other synthesis scales and instrumentation (Mermade 192).
  • Maintain inventory of chemicals and amidites for oligonucleotide synthesis.
  • Perform in-process and final analytics of oligonucleotide samples as needed.
  • Track progress, analyze, organize, and present data to team and cross-functionally.
  • Maintain a well-documented electronic laboratory notebook.
  • Actively participate in training activities and provide training to others as needed.
  • Author and review SOPs and technical reports.

Required Qualifications:

  • BS/MS with 1+ years experience in Chemistry, Biochemistry, Biotechnology, or related field.
  • Hands-on experience in the synthesis, purification, solid-liquid conjugation, and analysis of oligonucleotides.
  • Oligonucleotide process development experience is a plus.
  • Strong laboratory skills and experience in handling, troubleshooting and routine maintenance of lab equipment including automated synthesis platforms, HPLC and LC-MS etc.
  • High degree of flexibility and self-motivation in a fast-paced work environment with excellent organizational skills, ability to prioritize appropriately and meet deadlines.
  • Excellent interpersonal, communication and presentation skills.
  • Detail-oriented and excellent problem-solving abilities.
Benefits:  Korro offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance, a dependent care flexible spending account and a Company-funded health savings account and free parking.

Last updated on Oct 3, 2024

See more

About the company

More jobs at korrobio

Analyzing

Cambridge, Massachusetts

 · 

30+ days ago

Cambridge, Massachusetts

 · 

30+ days ago

Cambridge, Massachusetts

 · 

30+ days ago

Cambridge, Massachusetts

 · 

30+ days ago

Entwickelt von Blake und Linh in den USA und Vietnam.
We're interested in hearing what you like and don't like! Live chat with our founder or join our Discord
Änderungsprotokoll
🚀 LaunchpadNov 27
Erstellen Sie eine Website und verkaufen Sie Dienstleistungen basierend auf Ihrem Lebenslauf.
🔥 Dashboard für die JobsucheNov 13
Überarbeitete Benutzeroberfläche für die Jobsuche mit sortierbarem Raster, Live-Filterung, Lesezeichen und Bewerbungsverfolgung.
🫡 Anleitung zum AnschreibenSep 27
Neue Studio-Einstellungen geben Ihnen die Kontrolle über die KI-Ausgabe.
✨ Anschreiben StudioAug 9
Generieren Sie automatisch Anschreiben für jede Stelle.
🎯 Vorgeschlagene FilterAug 6
Copilot schlägt oberhalb der Ergebnisse zusätzliche Filter vor.
⚡️ Schnelle BewerbungenAug 2
Bewerben Sie sich mit Informationen aus Ihrem Lebenslauf auf Stellen. Erstmalige Abdeckung von ca. 200.000 Arbeitsplätzen in Spanien, Deutschland, Österreich, der Schweiz, Frankreich und den Niederlanden.
🧠 JobanalyseJul 12
Lassen Sie Copilot die Stellenbeschreibungen lesen und die wichtigsten Informationen herausfiltern, die Sie wissen möchten. Klicken Sie auf „Alle analysieren“, um es auszuprobieren. Klicken Sie auf das Zahnradsymbol des Copiloten, um die Eingabeaufforderung anzupassen.
© 2024 RemoteAmbitionAffiliate · Privacy · Terms · Sitemap · Status