Research Associate I/II - Binder Discovery

At A2, our mission is to extend the reach of cell therapy to tackle the next frontier in cancer treatment. Our team is dedicated to pushing the boundaries of science to transform medicine and turn the tide on serious illnesses. Central to achieving this mission is our focus on hiring and developing the best talent and building an environment that enables our team to do the best work of their careers and make an impact on patients and society at large.

We are seeking a highly motivated Research Associate to join our research team. In this role, you will design, execute and characterize the output from binder discovery campaigns to advance A2’s innovative Tmod™ cell therapy platform towards the clinic. You will be part of a highly collaborative cross-functional team of scientists, leading efforts to discover and develop transformative cell therapies.

The successful candidate will join us at our research facility in Agoura Hills, CA and work in a dynamic, fast-paced and team-oriented environment.

Requirements

Responsibilities include but are not limited to:

• Generate novel antibody based binding proteins from hybridoma and phage display technologies
• Work with scientists to design and perform cutting-edge in vitro and in vivo experiments to advance our Tmod cell therapy platform
• Collaborate to select, profile, and advance clinical candidates in a scientifically rigorous manner
• Work under supervisor’s guidance both independently and collaboratively to implement novel laboratory processes and solve technical problems

Basic Qualifications:

• Master’s or Bachelor’s degree in science including biology, biochemistry, immunology, bioengineering, or a related discipline
• 1-3 years of relevant lab experience (including during coursework studies)
• Willingness to learn and perform in vivo procedures on mice and/or rats
• Highly organized and capable of tracking multiple complex workflows
• Strong written and oral communication skills, with an ability to work in a dynamic, collaborative, and evolving environment

Preferred Qualifications and Experience:

• Hybridoma and/or phage display antibody discovery platform experience
• Experience in antibody screening and characterization using biochemical assays and quantitative analysis of protein-protein binding interactions (e.g. ELISA, FACS, Biacore, Octet, etc) is a plus
• Basic Molecular biology: PCR, DNA purification, cloning
• Experience designing, executing, and interpreting in vitro cell-based assays
• Hands-on experience with cell culture (mammalian and bacterial)
• Experience performing in vivo studies focused on hybridoma generation

Benefits

Benefits

At A2 Bio, every member of staff plays a critical role in ensuring we deliver on our mission. We recognize that delivering great science means investing in and developing our team. Our benefits programs are just one of the many ways we strive to help our employees take care of themselves and their families. We offer a variety of programs to help meet the needs of our diverse team and will continue to build on our offerings as we grow.

Benefits include:

• Competitive base salary and annual incentive opportunities (annual salary range for this position $67,000 - $85,000)
• Equity participation
• Medical, dental and vision benefits
• Life, disability and accident coverage
• Health and wellness programs
• Paid time off and holidays
• Flexible work arrangements
• Paid parental leave
• Environment where professional development is actively encouraged and supported.

A2 is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status or disability status.

Last updated on Jul 13, 2024