Large Molecule Biologics Analysis

Large Molecule Biologics Analysis needs 5-8 years of relevant laboratory experience working with mass spectrometry focused approaches utilizing proteomics and protein characterization workflows in a discovery setting to support drug development or biomarker discovery

Large Molecule Biologics Analysis requires:

• Experience operating, maintaining Sciex 7500 Qtrap, triple-quad mass spectrometers, or Orbitrap instruments. •

• Experience running nano-LCMS instruments for proteomics

• Experience with high throughput plate-based assays working on both large and small molecules. (Working with automation is a plus)

• Experience with analyzing and reporting analytical data, presenting data to colleagues and collaborators, and being a subject area expert in mass spec and analytical approaches.

• Cell Culture experience is a plus

• Experience with PK and Bio-Analysis of ADC drugs from complex matrices (plasma, tissue)

• Experience with R for data visualization is a plus. •

• Demonstrated can-do attitude and brings innovative ideas to challenging projects to contribute to a collaborative and cross-functional organization

• Minimum of a BSc with 8 years industry experience or MSc with 5 years industry experience in a mass spec focused lab on antibodies/proteins, and ADCs, or a PhD in a relevant scientific discipline.

• Strong interpersonal, communication, and organizational skills

• Experience with molecular biology, analytical techniques, and general lab practices, and presenting and interpreting complex datasets in Excel and Prism

• Extensive hands-on experience operating and maintaining LCMS instrumentation as well as SEC/HIC or U/HPLC systems, and proficient in the software used for data analysis (Protein Metrics, Skyline, Biopharma Finder)

• Experienced in analytical characterization using SEC/HIC, U/HPLC, cIEF, CE is a plus Ideal candidate will also have:

Large Molecule Biologics Analysis duties:

• Works independently to design and execute experiments, has a demonstrated track record at conceiving of creative solutions in the lab to answer complex questions, and is proficient in troubleshooting mass spec and LC systems from common vendors

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Last updated on Oct 17, 2024