Scholar Rock is a biopharmaceutical company that discovers, develops, and delivers life-changing therapies for people with serious diseases that have high unmet need. As a global leader in the biology of the transforming growth factor beta (TGFβ) superfamily of cell proteins and named for the visual resemblance of a scholar rock to protein structures, the clinical-stage company is focused on advancing innovative treatments where protein growth factors are fundamental. Over the past decade, the company has created a pipeline with the potential to advance the standard of care for neuromuscular disease, cardiometabolic disorders, cancer, and other conditions where growth factor-targeted drugs can play a transformational role.
Scholar Rock is the only company to show clinical proof of concept for a muscle-targeted treatment in spinal muscular atrophy (SMA). This commitment to unlocking fundamentally different therapeutic approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. By harnessing cutting-edge science in disease spaces that are historically under-addressed through traditional therapies, Scholar Rock works every day to create new possibilities for patients. Learn more about the company’s approach at ScholarRock.com and follow @ScholarRock and on LinkedIn.
Summary of Position:
The Sr. Manager/Associate Director of Safety Sciences will report to the Director of Safety Sciences and provide scientific, operational, and strategic leadership to support Scholar Rock’s pharmacovigilance (PV) and safety science activities. This individual will contribute to the evaluation, analysis, and management of safety data, ensuring compliance with regulatory standards and internal processes. Tasks include the creation and preparation of Development Safety Update Reports (DSURs), Signal detection presentations, safety board support documentation, and safety sections of investigator’s brochures, informed consent forms, study protocols, and health authority briefing books. The role involves collaboration across functional teams to support the development and safety evaluation of Scholar Rock’s products, particularly in early-stage neuromuscular, oncology, and cardiometabolic disorders. This is a unique opportunity for an enthusiastic and collaborative individual interested in contributing to the development of transformative products for patients with rare diseases. The position is remote-based within the U.S.