The Senior Scientist, PSC Biology will be a strategic and technical leader of a team responsible for developing, testing, and implementing novel NGS (epi-) genome sequencing technologies to characterize human pluripotent stem cells (hPSCs) and their differentiated progeny at the molecular, (epi-) genomic level. This includes the use of NGS technologies to evaluate on- and off-target gene editing analysis of genome engineered PSCs. They will work independently and collaboratively participate in efforts to generate and analyze different types of sequencing data to gain further knowledge of PSC pluripotent state and their differentiation potential.
They will also support and guide colleagues and their activities on the team, consistent with team leadership aligned program goals. Hands-on wet-lab experience with NGS sequencing technologies (nucleic acid extractions, sequencing library preparation, etc.) as well as a strong theoretical background in (human) genetics is essential; strong background in stem cell biology is preferred. Experience with hPSC culture, CRISPR/Cas-based genome engineering, and bioinformatics is strongly preferred. The incumbent will work closely with several collaborating teams, including through roles representing the team in cross-functional settings.
This is an outstanding opportunity for a talented individual to contribute to bringing a new class of medicines to patients and gain valuable career experience in the cell therapy space. Collaboration with a highly motivated, world-class team of scientists and engineers promises an exciting and engaging work environment for motivated candidates.