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Senior Process Development Scientist, Molecular Biology

elegen · 30+ days ago
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Elegen is blazing a path towards a biology-based economy with a highly innovative approach to DNA synthesis that delivers an industry leading length of 7kb in 7 business days with a 99.999% per base accuracy. Our multidisciplinary team of best-in-class biologists, chemists, hardware, and software engineers apply cutting-edge technologies and methods to solve critical bottlenecks in synthetic biology workflows to help our customers in pharma, biotech, agbio, and biomanufacturing streamline their work and realize the full potential of programmable biology.

At Elegen, we are developing innovative technologies to unlock the SynBio revolution. We are seeking a scientist or engineer passionate about advancing biology via lab automation to become one of the founding members of our growing R&D team. As a part of our team, they will play a central role in automating molecular biology workflows for scalable production of long, perfect synthetic DNA.

This is a rare and exciting opportunity for a highly motivated and self-driven candidate to get in near the ground floor of a fast moving, very high impact start-up. In addition to working on cutting edge technology, the candidate would help us establish a strong culture of mutual respect, integrity, and collaboration while working alongside some of Silicon Valley’s best scientists and engineers.

Key Responsibilities:

  • Study and analyze processes as designed, model process behaviors, and help identify key metrics.
  • Translate bench scale methods into an automatable form.
  • Analyze large data sets to improve process steps (efficiency, cost and throughput) and product (quality, yield, format).
  • Help identify major areas of improvement and provide framework (ranges, metrics, requirements) for new process designs, outline/design experiments for this purpose.
  • Clearly communicate findings to the core team, and other functional teams in the organization.
  • Collaborate in process transfer for commercial scale manufacturing, partner with the Production, Automation and Software teams to troubleshoot process and method, rigorously monitor processes post transfer for a limited number of runs.

Essential Qualifications and Experience:

  • PhD in the life sciences one, with 5+ years of hands-on molecular biology experience in assay, product, and/or process development.
  • High proficiency in applied statistics, and understanding of fundamental concepts in statistical analysis.
  • Experience developing molecular biology/biochemistry assays from conception through data analysis.
  • Previous experience with process modeling and implementation of process improvements.
  • Programming experience (R/Python/other, GitHub links if available) for developing custom modeling capabilities.
  • Experience with nucleic acid purification, quantification and qualification, molecular cloning, PCR, and NGS sequencing.
  • Excellent written and verbal communication skills.

Preferred Qualifications and Experience:

  • Experience working with large data sets, and communicating data (visual communication skills a plus)
  • Team player with experience of cross-functional collaborations.

Salary and Benefits:

The annual base salary compensation for this role, if based in California is: $140,000 - $170,000. Compensation may be different in other locations.  Final compensation also includes bonus, equity and benefits.   Specific offer packages are determined by multiple factors, including candidate skill, experience, expertise, and location. 

✓ Healthcare    ✓ Dental    ✓ Vision    ✓ Learning Allowance

✓ 401K    ✓ Flexible PTO   ✓ Short Term Disability    ✓ Fitness Allowance

 

About The Company:

Founded and led by Dr. Matthew Hill and located in San Carlos, CA, Elegen is well-capitalized by top life science investors, including Andreessen Horowitz, 8VC, and KdT. The company is advised and staffed by leading biotechnology scientists and entrepreneurs, including Dr. Marc Unger, inventor of the Nanoflex™ valve, and former CSO of Fluidigm. Dr. Hill has a PhD from Stanford and a proven track record of advancing innovative technologies from invention to commercial success. Over eight years in his previous role as VP of R&D at a leading molecular diagnostics company, he co-invented and launched five precision molecular diagnostic products, including a best-in-class noninvasive prenatal test used by millions. These products earn more than $350 million per year in revenue and enabled an IPO.

Elegen is an Equal Opportunity Employer.

Elegen provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.  All applicants have rights under the following Federal Employment Laws: 

Last updated on Aug 16, 2024

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